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Early intervention benefits patients with multiple sclerosis


Early treatment has long-lasting effects on MS activity, researchers found in a study published in the Aug. issue of Neurology, a medical journal from the American Academy of Neurology. According to a Newswise press release, researchers studied 468 patients randomly assigned to receive either early treatment or placebo.

After participants were diagnosed with MS or after two years, the participants could switch from placebo to an interferon beta-1b drug or something similar, the press released stated. After 11 years, researchers reevaluated the 278 who remained in the study. Those who had early treatment were 33% less likely to be diagnosed with MS than those who received delayed treatment, according to the study.

“Overall, early treatment appears to have a benefit on relapses, especially early in the disease, but limited effects on other outcome measures, including outcomes reported by patients,” said Brian C. Healy, PhD, in the press release. Healy is on staff at Brigham and Women’s Hospital and Massachusetts General Hospital in Boston and a member of the American Academy of Neurology, who wrote an accompanying editorial.

Results of the study showed that people in the early group had more time before their first relapse of the disease than people in the delayed group — 1,888 days compared with 931 days. The early group’s overall yearly relapse rate was 0.21 compared to 0.26 in the delayed group.

The April 2016 MD Magazine Peer Exchange video, “Importance of Early Intervention in Multiple Sclerosis” featured Patricia K. Coyle, MD, professor and vice chairwoman (Clinical Affairs) and director of the Multiple Sclerosis Comprehensive Care Center at Stony Brook University Medical Center, New York. “Virtually every single study has said that if you look at early treatment — as opposed to delayed treatment — and you look at late consequences, the early-treated groups are doing better,” she said in the video. “I think in a paradigm of accumulating permanent injury that is the best possibility of truly changing the natural history of the disease — to stop that damaged paradigm as much as you can in its tracks, early.”

According to the WebMD website, people may begin to show signs of the disease between ages 20 and 40. Sometimes several years can pass between episodes. The website lists MRI, spinal tap and evoked potentials as possible tests to diagnose the disease.

“Getting an MS diagnosis can be a lengthy process,” the website stated. “When some people finally learn they have the condition after months or years of symptoms, they take the news as something of a relief. For others, it can be shocking.”

The initial symptom often is blurred or double vision, red-green color distortion or even blindness in one eye, according to the American Academy of Neurology website. “Most MS patients experience muscle weakness in their extremities and difficulty with coordination and balance,” the website stated. “These symptoms may be severe enough to impair walking or even standing. In the worst cases, MS can produce partial or complete paralysis.”

According to the National MS Society website, more than 2.3 million people are affected by MS worldwide, “because symptoms can be completely invisible, the prevalence of MS in the U.S. can only be estimated,” the site stated.

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By | 2020-04-15T16:42:08-04:00 September 9th, 2016|Categories: Nursing News|Tags: |4 Comments

About the Author:

Sallie Jimenez
Sallie Jimenez is content manager for healthcare for from Relias. She develops and edits content for the blog, which covers industry news and trends in the nursing profession and healthcare. She also develops content for the Digital Editions. She has more than 25 years of healthcare journalism, content marketing and editing experience.


  1. Avatar
    Carol Dover September 10, 2016 at 5:44 am - Reply

    How can I receive information about MS?

  2. Avatar
    Ambrosia Merolize August 29, 2018 at 4:13 am - Reply

    I was diagnosed with Multiple Sclerosis (MS) in October 2011, at the age of 55. I woke up one morning with numbness in my lower back and legs, I couldn’t feel my feet touching the floor. I saw my doctor and had an MRI to see if I had a disc problem, it was negative and she told me she feared MS. I was sent to a neurologist, had two more MRIs, and was told that night that I have four lesions on my spine MS. I tried every shots available but nothing worked. In 2015, my neurologist and I decided to go with natural treatment and was introduced to Natural Herbal Gardens natural organic MS Herbal formula, i had a total decline of symptoms with this treatment, the numbness, terrible back pains, stiffness, body weakness, double vision, depression and others has subsided. Visit Natural Herbal Gardens official website ww w. naturalherbalgardens. com. This treatment is a breakthrough for all suffering from Multiple sclerosis, i am strong again!

  3. Avatar
    Finlay Cedar February 27, 2019 at 7:07 am - Reply

    Been diagnosed with multiple sclerosis in 2015, and I was a woman of 50. They put me on Rebif which I took until 2017 and was switched to Copaxone. I had two relapses on Rebif, none so far on Copaxone. I do notice my balance was getting worse, and my memory, as well as erectile dysfunction and spasms’ had no choice to sick for other solution and I was introduce to totalcureherbsfoundation com  which I purchase the MS herbal formula from the foundation, the herbal supplement has effectively get rid of my multiple sclerosis and reversed all symptoms. 

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