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Nurses Drug Handbook by Nursing Spectrum and Nurse Week

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Drug Handbook Home > Safe Drug Administration >
Tablets and Capsules NOT to Crush

Crushing extended-release or other long-acting oral drug forms can cause the ingredients to be released all at once instead of gradually. Similarly, crushing can break the coating of enteric-coated drugs, leading to GI irritation. Other drugs may taste bad or have carcinogenic or teratogenic potential when crushed. Never crush the trade-name drugs listed below.

Accutane Nexium
Aciphex Nia-Bid
Adalat CC Niaspan
Aerolate Nicotinic Acid
Aggrenox Nitro-Bid
Allegra D Nitroglyn
Artane Sequels Nitrong
Arthrotec Nitrostat
Asacol Norflex
Bayer EC Norpace CR
Bellergal-S Novafed A
Biaxin XL Oramorph SR
Boniva OxyContin
Calan SR Pancrease MT
Carbatrol PCE
Carbiset-TR Pentasa
Cardene SR Perdiem
Cardizem CD, LA, SR Phazyme
Carter’s Little Pills Phyllocontin
Cartia XT Plendil
Ceclor CD Pneumomist
CellCept Prelu-2
Choledyl SA Prevacid
Claritin-D Prilosec
Colace Pro-Banthine
Colestid Procainamide HCL SR
Compazine Spansules Procardia
Concerta Proscar
Cotazym-S Protonix
Covera-HS Proventil Repetabs
Creon Prozac
Cytovene Quibron-T/SR
Cytoxan Quinaglute Dura-Tabs
Deconamine SR Quinidex Extentabs
Depakene Respaire SR
Depakote Respbid
Desoxyn Gradumets Reyataz
Dexedrine Spansule Ritalin-SR
Diamox Sequels Roxanol SR
Dilacor XR Ru-Tuss
Dilatrate-SR Sinemet CR
Disobrom Slo-bid Gyrocaps
Ditropan XL Slo-Niacin
Donnatal Extentabs Slo-Phyllin GG, Gyrocaps
Donnazyme Slow FE
Drixoral Slow-K
Dulcolax Slow-Mag
DynaCirc CR Sorbitrate SA
Easprin Striant
Ecotrin Sudafed 12 Hour
Effexor XR Sular
Entex LA Sustaire
Erythromycin Base Tavist-D
Eskalith CR Tegretol-XR
Factive Teldrin
Feocyte Ten-K
Feosol Tenuate Dospan
Ferro-Sequel Tessalon Perles
Feratab Theobid Duracaps
Flomax Theochron
Glucotrol XL Theoclear LA
Guaifed Theo-Dur
Ilotycin Theolair-SR
Imdur Theo-Sav
Inderal LA Theospan-SR
Inderide LA Theo-24
Indocin SR Theovent
Isoptin SR Theo-X
Isordil Sublingual, Tembids Thorazine Spansules
Isosorbide Dinitrate Sublingual Tiazac
Kadian Toprol XL
Kaon-Cl T-Phyl
K-Dur Tranxene-SD
Klor-Con Trental
Klotrix Triaminic
K-Tab Trilafon Repetabs
Levbid Trinalin Repetabs
Levsinex Timecaps Tuss-Ornade Spansules
Lexxel Tylenol Extended Relief
Lithobid Ultrase MT
Lodine XL Uniphyl

Lodrane LD

Verelan
Macrobid Volmax
Mestinon Timespans Voltaren, XR
Methylin ER Wellbutrin SR, XL
Micro-K Extencaps Xanax-XR
Monafed ZORprin
MS Contin Zyban
Naldecon Zymase
Naprelan
 



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